January 30, 2012 8:30 AM, EST

Stretch of I-75 Closed Following Deadly Weekend Pileup in Fla.

Florida state police were investigating a huge weekend pileup on Interstate 75 near Gainesville, Fla., that killed 10 people as cars and trucks drove into dense fog and smoke, and a section of the highway remained closed Monday, news services reported.

The 19-vehicle crash, which occurred before dawn Sunday, also sent 18 people to the hospital, the Orlando Sentinel reported Monday on its website.

State troopers had opened northbound lanes of I-75 Sunday night but closed them again Monday due to low visibility from smoke and fog, the Sentinel reported.

Officials were investigating the cause of the smoke that led to the accidents, news reports said.

I-75 was closed in both directions early Monday from mile maker 358 to mile marker 384, the Florida Department of Transportation said on its website, in urging motorists to use caution.

US-27 near Williston, Fla., was congested due to overflow from the highway closure, FDOT said.